This means that even in the absence of oxygen, tumor cells can extract energy from glucose molecules. Rapid cell division of cancer cells to fuel growth requires the presence of a lot of sugar. Warburg believed a defect in the mitochondria of cancer cells allows the cells to use glycolysis to fuel growth, which suggests cancer is actually a metabolic disease that is affected by your diet.
Research Supports Cancer Is a Metabolic Disease
In the U.S. an estimated 600,000 people will die from cancer this year, costing over $125 billion in health care expenses.9 The World Health Organization finds cancer is the second leading cause of death worldwide, responsible for nearly 8.8 million deaths in 2015.10 Imagine if that many people were dying each year from the flu or polio.
This would be headline news each day. Have we become so used to the idea of cancer that 1.6 million new cases every year in the U.S. is old news?
Conventional cancer treatment focuses on surgery, chemotherapy and radiation. However, many of these treatments have only been successful at lengthening lives by months and not in curing the disease.
The basis for these treatments is that cancer is a genetic problem and not one triggered and fed by mitochondrial dysfunction. As a result, the nutritional link is typically overlooked.
The featured study exposes the flaw in using only pharmaceutical, surgical and radiation treatments on tumors and other cancer growths.
Warburg postulated that by cutting off the food supply cancer cells rely on for survival, you effectively starve them.
Research has also shown that genetic mutations are not the trigger for cancer growths but rather a downstream effect resulting from defective energy metabolism in cell mitochondria. This defective energy metabolism changes the way your cells function and promotes the growth of cancer cells.
In other words, if your mitochondria remain healthy, your risk of developing cancer is slim. Thomas Seyfried, Ph.D., author of “Cancer as a Metabolic Disease: On the Origin, Management and Treatment of Cancer,” has received many awards and honors through his long and illustrious career for the work he’s done expanding knowledge of how metabolism affects cancer.
He is one of the pioneers in the application of nutritional ketosis for cancer. While in nutritional ketosis, your body burns fat for fuel instead of starches and carbohydrates. By eating a healthy high-fat, low-carbohydrate and low- to moderate-protein diet, your body begins to burn fat as its primary fuel. Research from Ohio State University demonstrates athletes who eat a ketogenic diet experience significant improvements in their health and performance.11
Nutritional ketosis is also showing great promise in the treatment of neurological disorders such as Alzheimer’s disease or Parkinson’s disease,12 Type 2 diabetes13 and seizures14 that are unresponsive to medications. This recent research from Belgium confirms the work Warburg, Seyfried and others have done, and supports the hypothesis that cancer is a metabolically based disease and not a genetic problem.
Chemotherapy May Not Be the Answer
Traditional administration of chemotherapy may increase your risk of metastasis (the spread of cancer cells through your body) and may trigger additional tumor growth. Chemotherapy is sometimes recommended prior to surgery to help shrink the size of the tumor, increasing the likelihood a woman could have a lumpectomy instead of a full mastectomy.
Recent research reveals that giving chemotherapy prior to breast cancer surgery may promote metastasis of the disease, allowing it to spread to other areas of your body.15 This greatly increases the risk of dying. The study found that mice had twice the amount of cancer cells in their blood and lungs after treatment with chemotherapy. The researchers also found similar results in 20 human patients whose tumor microenvironments became more favorable to metastasis after chemotherapy.